This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations:
CD47 antigen,CD47 antigen (Rh-related antigen, integrin-associated signal transducer),CD47 glycoprotein,Rh-related antigen,antigen identified by monoclonal antibody 1D8,antigenic surface determinant protein OA3,integrin associated protein,integrin-associa