< 1 EU per 1 ug of protein (determined by LAL method)
Activity:
Measured by the ability of the immobilized protein to support the adhesion of U937 Human histiocytic lymphoma cells. When cells are added to VCAM1 coated plates 10 ug/mL. This effect is more to 70%.
Quality Control Testing:
3 ug by SDS-PAGE under reducing condition and visualized by Coomassie blue stain.
Storage Buffer:
In Phosphate-Buffer Saline pH 7.4 (10% glycerol)
Storage Instruction:
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Aliquot to avoid repeated freezing and thawing.
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq