Specific activity is > 4000 pmol/min/mg, and is defined as the amount of enzyme that catalyze the reduction of 1.0 pmole cytochrome C by NADPH per minute at pH8.0 at 25°C.
Quality Control Testing:
SDS-PAGE Stained with Coomassie Blue.
SDS-PAGE analysis of PRO (Human) Recombinant Protein.
Recommend Usage:
Biological Activity SDS-PAGE The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.4 (10% glycerol)
Storage Instruction:
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq