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Last updated: 2023/3/19

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PON1 (Human) Recombinant Protein BioActive

  • Catalog # : P6980
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  • Specification
  • Product Description:
  • Human PON1 (NP_000437, 16 a.a.- 355 a.a.) partial recombinant protein with C-terminal His tag expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 39
  • Form:
  • Liquid
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU per 1 ug of protein (determined by LAL method).
  • Activity:
  • Specific activity is > 2,500 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1 pmole of p-nitrophenyl acetate to p-nitrophenol per minute at pH7.5 at 37°C.
  • Quality Control Testing:
  • 3 ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6980
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (20% glycerol).
  • Storage Instruction:
  • Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 5444
  • Gene Name:
  • PON1
  • Gene Alias:
  • ESA,PON
  • Gene Description:
  • paraoxonase 1
  • Gene Summary:
  • The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq
  • Other Designations:
  • arylesterase B-type,esterase A,paraoxonase B-type,serum aryldiakylphosphatase
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