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Last updated: 2023/3/19

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IDO1 (Human) Recombinant Protein BioActive

  • Catalog # : P6947
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  • Specification
  • Product Description:
  • Human IDO1 (NP_002155, 1 - 403 a.a.) full length recombinant protein with His tag expressed in Escherichia coli expression system
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 47.7
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU/ug
  • Activity:
  • Specific activity is > 300 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0 pmole of L-Tryptophan to N-formyl-L-kynurenine per minute at pH 6.5 at 25°C.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P6947
    3 ug SDS-PAGE under reducing condition and visualized by coomassie blue stain.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl, 0.15 M NaCl, 1 mM DTT, pH 8.0 (20% glycerol)
  • Storage Instruction:
  • Store at 4°C for one week. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3620
  • Gene Name:
  • IDO1
  • Gene Alias:
  • CD107B,IDO,INDO
  • Gene Description:
  • indoleamine 2,3-dioxygenase 1
  • Gene Summary:
  • Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM
  • Other Designations:
  • indole 2,3-dioxygenase,indoleamine-pyrrole 2,3 dioxygenase
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