Human TNFRSF17 (NP_001183.2, 1 a.a. - 54 a.a.) partial recombinant protein with a Fc, 6×His tag at the C-terminus expressed in HEK293 cells.
Host:
Human
Form:
Lyophilized
Preparation Method:
Mammalian cell (HEK293) expression system
Purification:
Ni-sepharose purification
Purity:
> 92% (determined by SDS-PAGE)
Endotoxin Level:
< 0.1 EU/ug of protein (determined by LAL method)
Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human TNFSF13B at 5 ug/mL (100 uL/well) can bind recombinant human TNFRSF17 with a linear range of 3-20 ng/mL.
Quality Control Testing:
SDS-PAGE Stained with Coomassie Blue
Recommend Usage:
SDS-PAGE The optimal working dilution should be determined by the end user.
Storage Buffer:
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Storage Instruction:
Store at -80°C on dry atmosphere, lyophilized antibodies are stable at least 2 years. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq
Other Designations:
B cell maturation antigen,B-cell maturation factor,OTTHUMP00000160261