CTSC monoclonal antibody, clone 14
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant CTSC.
Immunogen
Recombinant protein corresponding to full length human CTSC.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes recombinant protein CTSC.
Form
Liquid
Purification
Affinity purification
Concentration
1 ug/uL
Isotype
IgG2b
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis in CTSC recombinant protein with CTSC monoclonal antibody, clone 14 (Cat # MAB8780) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CTSC
Entrez GeneID
1075Protein Accession#
NM_001814.4Gene Name
CTSC
Gene Alias
CPPI, DPP1, DPPI, HMS, JP, JPD, PALS, PLS
Gene Description
cathepsin C
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cathepsin J|dipeptidyl transferase|dipeptidyl-peptidase I
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Interactome
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Disease
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