CD69 monoclonal antibody, clone HP-4B3
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Specification
Product Description
Mouse monoclonal antibody raised against native CD69.
Immunogen
Native purified CD69 from IL-2 activated human NK cells.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — CD69
Entrez GeneID
969Gene Name
CD69
Gene Alias
CLEC2C
Gene Description
CD69 molecule
Omim ID
107273Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants
Other Designations
C-type lectin domain family 2, member C|CD69 antigen (p60, early T-cell activation antigen)
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Interactome
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Disease
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Publication Reference
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Characterization of distinct stages during the differentiation of human CD69+CD3+ thymocytes and identification of thymic emigrants.
Vanhecke D, Leclercq G, Plum J, Vandekerckhove B.
Journal of Immunology 1995 Aug; 155(4):1862.
Application：Flow Cyt, Mouse, Mouse thymocytes.
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The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells.
Testi R, D'Ambrosio D, De Maria R, Santoni A.
Immunology Today 1994 Oct; 15(10):479.
Application：Flow Cyt, Human, Mouse, Hematopoietic cells.
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The activation antigen CD69.
Ziegler SF, Ramsdell F, Alderson MR.
Stem Cells 1994 Sep; 12(5):456.
Application：Flow Cyt, Human, Mouse, B cells, Myeloid cells, Natural killer cells, Platelets, T cells, Thymocytes.
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Characterization of distinct stages during the differentiation of human CD69+CD3+ thymocytes and identification of thymic emigrants.
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