CD7 monoclonal antibody, clone 3Ale
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against native CD7.
Immunogen
Native purified CD7 from human HSB2-T cells.
Host
Mouse
Reactivity
Human
Specificity
This antibody induces T cell transmembrane calcium flux.
Form
Liquid
Isotype
IgG2b
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — CD7
Entrez GeneID
924Gene Name
CD7
Gene Alias
GP40, LEU-9, TP41, Tp40
Gene Description
CD7 molecule
Omim ID
186820Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq
Other Designations
CD7 antigen|CD7 antigen (p41)|T-cell antigen CD7|T-cell leukemia antigen|p41 protein
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Interactome
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Pathway
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Publication Reference
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Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.
Ware RE, Hart MK, Haynes BF.
Journal of Immunology 1991 Oct; 147(8):2787.
Application：Flow Cyt, Human, Human T cells.
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Characterization of the surface topography and putative tertiary structure of the human CD7 molecule.
Ware RE, Scearce RM, Dietz MA, Starmer CF, Palker TJ, Haynes BF.
Journal of Immunology 1989 Dec; 143(11):3632.
Application：Blocking, IP, WB-Ce, Human, HSB cells, Synthetic peptides.
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Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.
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