Cacna1d monoclonal antibody, clone S48
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of human cell line mixed lysate with Cacna1d monoclonal antibody, clone S48 (Cat # MAB6648).
Immunofluorescence
Immunofluorescence staining with Cacna1d monoclonal antibody, clone S48 (Cat # MAB6648).
Image A, human hippocampus.
Image B, mouse backskin.
Image C, mouse backskin.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant Cacna1d.
Immunogen
Recombinant fusion protein corresponding to amino acids 859-875 of rat Cacna1d.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
Detects ~250KDa. No cross-reactivity against Cav1.2.
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
Western Blot (1-10 ug/mL)
Immunohistochemistry (0.1-1.0 ug/mL)
Immunocytochemistry (0.1-1.0 ug/mL)
Immunofluorescence (1.0-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human cell line mixed lysate with Cacna1d monoclonal antibody, clone S48 (Cat # MAB6648).Immunocytochemistry
Immunofluorescence
Immunofluorescence staining with Cacna1d monoclonal antibody, clone S48 (Cat # MAB6648).
Image A, human hippocampus.
Image B, mouse backskin.
Image C, mouse backskin.Immunoprecipitation
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Gene Info — Cacna1d
Entrez GeneID
29716Protein Accession#
P27732Gene Name
Cacna1d
Gene Alias
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Gene Description
calcium channel, voltage-dependent, L type, alpha 1D subunit
Gene Ontology
HyperlinkGene Summary
calcium channel
Other Designations
CaV1.3alpha1|calcium channel alpha-1 subunit|voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker
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Publication Reference
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Congenital long QT syndrome.
Crotti L, Celano G, Dagradi F, Schwartz PJ.
Orphanet Journal of Rare Diseases 2008 Jul; 3:18.
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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT.
Cell 2004 Oct; 119(1):19.
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Congenital long QT syndrome.
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