CREB1 (phospho S133) monoclonal antibody, clone B1C4
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic phosphopeptide of CREB1.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S133 of human CREB1.
Host
Mouse
Reactivity
Human
Specificity
Reactive to the immunogen, peptide-BSA conjugating and peptide in ELISA.
Form
Lyophilized
Isotype
IgG2, kappa
Recommend Usage
ELISA (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 10 mM PBS, pH 7.0
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CREB1
Entrez GeneID
1385Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
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Interactome
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Pathway
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Disease
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