CD4 monoclonal antibody, clone RFT4
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Specification
Product Description
Mouse monoclonal antibody raised against native CD4.
Immunogen
Native purified CD4 human thymocytes and E-rosetted lymphocytes.
Host
Mouse
Reactivity
Human
Specificity
human CD4.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — CD4
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Interactome
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Pathway
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Disease
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Publication Reference
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The two membrane proximal domains of CD4 interact with the T cell receptor.
Vignali DA, Carson RT, Chang B, Mittler RS, Strominger JL.
The Journal of Experimental Medicine 1996 May; 183(5):2097.
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The CD4 molecule. Roles in T lymphocytes and in HIV disease. Introduction.
Littman DR.
Curr Top Microbiol Immunol 1996 Jan; 205.
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Molecular recognition of antigen involves lattice formation between CD4, MHC class II and TCR molecules.
Sakihama T, Smolyar A, Reinherz EL.
Immunology Today 1995 Dec; 16(12):581.
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The two membrane proximal domains of CD4 interact with the T cell receptor.
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