CD2 monoclonal antibody, clone LT2 (FITC)
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More Files
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Flow Cytometry
Surface staining of human peripheral blood cells with CD2 monoclonal antibody, clone LT2 (FITC) (Cat # MAB4382). Cells in the lymphocyte gate were used for analysis.
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Specification
Product Description
Mouse monoclonal antibody raised against native CD2.
Immunogen
Native purified CD2 from normal human blood lymphocytes.
Host
Mouse
Theoretical MW (kDa)
50
Reactivity
Human
Specificity
This antibody LT2 reacts with CD2, a 50 KDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
Form
Liquid
Conjugation
FITC
Isotype
IgG2a
Recommend Usage
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Flow Cytometry
Surface staining of human peripheral blood cells with CD2 monoclonal antibody, clone LT2 (FITC) (Cat # MAB4382). Cells in the lymphocyte gate were used for analysis. -
Gene Info — CD2
Entrez GeneID
914Gene Name
CD2
Gene Alias
SRBC, T11
Gene Description
CD2 molecule
Omim ID
186990Gene Ontology
HyperlinkGene Summary
sheep red blood cell receptor|OTTHUMP00000024366|OTTHUMP00000059318|lymphocyte-function antigen-2
Other Designations
CD2 antigen (p50), sheep red blood cell receptor|OTTHUMP00000024366|OTTHUMP00000059318|lymphocyte-function antigen-2
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Interactome
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Pathway
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Disease
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Publication Reference
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CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection.
Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC.
World Journal of Gastroenterology 2007 Aug; 13(31):4207.
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Mechanisms of Cellular Avidity Regulation in CD2-CD58-Mediated T Cell Adhesion.
Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE.
ACS Chemical Biology 2006 Nov; 1(10):649.
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[A panel of monoclonal antibodies against human lymphocyte antigens].
Filatov AV, Bachurin PS, Markova NA, Surnakova NE.
Eksp Onkol 1989 Jan; 11(2):28.
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CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection.
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