Flow cytometric analysis of HeLa cells with HSPB1 (phospho S82) monoclonal antibody, clone CB2 (PE) (Cat # MAB23514). Unstained as negative control (blue) or untreated (red) or treated with UV and TPA (green).
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq
Other Designations:
OTTHUMP00000024846,estrogen-regulated 24 kDa protein,heat shock 27kD protein 1,heat shock protein beta-1,stress-responsive protein 27