MAPKAPK2 (phospho T334) monoclonal antibody, clone H2 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of C6 cells with MAPKAPK2 (phospho T334) monoclonal antibody, clone H2 (APC) (Cat # MAB23454). Treated with staurosporine (red) or treated with UV+TPA (green) or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells treated with staurosporine (black) or treated with UV+TPA (blue).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human MAPKAPK2.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding T334 of human MAPKAPK2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
APC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of C6 cells with MAPKAPK2 (phospho T334) monoclonal antibody, clone H2 (APC) (Cat # MAB23454). Treated with staurosporine (red) or treated with UV+TPA (green) or concentration-matched Rabbit (G9) mAb IgG Isotype Control (APC Conjugate) for cells treated with staurosporine (black) or treated with UV+TPA (blue). -
Gene Info — MAPKAPK2
Entrez GeneID
9261Gene Name
MAPKAPK2
Gene Alias
MK2
Gene Description
mitogen-activated protein kinase-activated protein kinase 2
Omim ID
602006Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034531|OTTHUMP00000034532
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Interactome
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Pathway
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