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Last updated: 2023/3/26

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CRKL (phospho Y207) monoclonal antibody, clone G4 (APC) 

  • Catalog # : MAB23433
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human CRKL
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding Y207 of human CRKL.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Conjugation:
  • APC
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (5 uL/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of K-562 cells with CRKL (phospho Y207) monoclonal antibody, clone G4 (APC) (Cat # MAB23433). Unstained treated with imatinib as negative control (blue) or stained treated with imatinib (red) or treated with pervanadate (green).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1399
  • Gene Name:
  • CRKL
  • Gene Alias:
  • -
  • Gene Description:
  • v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  • Gene Summary:
  • This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic
  • Other Designations:
  • v-crk avian sarcoma virus CT10 oncogene homolog-like
  • Interactome
  • Interactome
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