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MAPK14 (phospho T180/Y182) monoclonal antibody, clone E3 (SureLight 488) 

  • Catalog # : MAB23422
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human MAPK14.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding T180/Y182 of human MAPK14.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Conjugation:
  • SureLight 488
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (5 uL/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of C6 cells with MAPK14 (phospho T180/Y182) monoclonal antibody, clone E3 (SureLight 488) (Cat # MAB23422). Unstained and untreated (blue) or stained and untreated (red) or stained and treated with staurosporine (green).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1432
  • Gene Name:
  • MAPK14
  • Gene Alias:
  • CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA
  • Gene Description:
  • mitogen-activated protein kinase 14
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • Csaids binding protein,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,p38 MAP kinase,p38 mitogen activated protein kinase,p38alpha Exip,stress-activated protein kinase 2A
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