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SATA5A/STAT5B (phospho Y694) monoclonal antibody, clone G11 (FITC) 

  • Catalog # : MAB23402
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SATA5A/STAT5B.
  • Immunogen:
  • A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (5 uL/million cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% NaN3, 0.2% BSA)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of NIH3T3 cells with SATA5A/STAT5B (phospho Tyr694) monoclonal antibody, clone G11 (FITC)(Cat # MAB23402). Treated with imatinib (red) or treated with pervanadate (green)
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 6776
  • Protein Accession#:
  • P42229; P51692
  • Gene Name:
  • STAT5A
  • Gene Alias:
  • MGF,STAT5
  • Gene Description:
  • signal transducer and activator of transcription 5A
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq
  • Other Designations:
  • -
  • Gene Information
  • Entrez GeneID:
  • 6777
  • Protein Accession#:
  • P42229; P51692
  • Gene Name:
  • STAT5B
  • Gene Alias:
  • STAT5
  • Gene Description:
  • signal transducer and activator of transcription 5B
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq
  • Other Designations:
  • transcription factor STAT5B
  • Interactome 1
  • Interactome
  • Interactome 2
  • Interactome
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