NPM1 (phospho S4) monoclonal antibody, clone A1

Catalog # MAB23394

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Quantity

Size:200 uL
Price: USD $ 747.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot
Application

Western Blot

Flow cytometric analysis of C6 cells with NPM1 (phospho Ser4) monoclonal antibody, clone A1(Cat # MAB23394). Untreated (red) or treated with nocodazole (green)

Flow Cytometry
Application

Flow Cytometry

Flow cytometric analysis of C6 cells with NPM1 (phospho Ser4) monoclonal antibody, clone A1(Cat # MAB23394). Untreated (red) or treated with nocodazole (green).

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic phosphopeptide of human NPM1.

    Immunogen

    A synthetic phospho-peptide corresponding to residues surrounding Ser4 of human phospho-NPM

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Isotype

    IgG1, kappa

    Recommend Usage

    Flow Cytometry (5 uL/million cells)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS (0.02% NaN3, 0.1% BSA, 50% Glycerol)

    Storage Instruction

    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

    Flow cytometric analysis of C6 cells with NPM1 (phospho Ser4) monoclonal antibody, clone A1(Cat # MAB23394). Untreated (red) or treated with nocodazole (green)

    Flow Cytometry

    Flow cytometric analysis of C6 cells with NPM1 (phospho Ser4) monoclonal antibody, clone A1(Cat # MAB23394). Untreated (red) or treated with nocodazole (green).
  • Gene Info — NPM1

    Entrez GeneID

    4869

    Protein Accession#

    P06748

    Gene Name

    NPM1

    Gene Alias

    B23, MGC104254, NPM

    Gene Description

    nucleophosmin (nucleolar phosphoprotein B23, numatrin)

    Omim ID

    164040 601626

    Gene Ontology

    Hyperlink

    Gene Summary

    NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM

    Other Designations

    nucleolar phosphoprotein B23|nucleophosmin 1|nucleophosmin/nucleoplasmin family, member 1|numatrin

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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