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Last updated: 2023/3/26

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MCM2 (phospho S139) monoclonal antibody, clone B12 (PE) 

  • Catalog # : MAB23387
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human MCM2.
  • Immunogen:
  • A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho MCM2
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (5 uL/million cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% NaN3, 0.2% BSA)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of C6 cells with MCM2 (phospho Ser139) monoclonal antibody, clone B12 (PE)(Cat # MAB23387). Unstained as negative control (blue) or untreated (red) or treated with staurosporine (green)
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 4171
  • Gene Name:
  • MCM2
  • Gene Alias:
  • BM28,CCNL1,CDCL1,D3S3194,KIAA0030,MGC10606,MITOTIN,cdc19
  • Gene Description:
  • minichromosome maintenance complex component 2
  • Gene Summary:
  • The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor MCM2,MCM2 minichromosome maintenance deficient 2, mitotin,cell devision cycle-like 1,cyclin-like 1,minichromosome maintenance deficient 2 (mitotin),nuclear protein BM28
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