H2AX (phospho S139) monoclonal antibody, clone 1E4 (APC)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of 293T cells with H2AX (phospho Ser139) monoclonal antibody, clone 1E4 (APC)(Cat # MAB23361). Unstained as negative control (blue) or untreated (red) or treated with UV and TPA (green).
-
Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human H2AX.
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
APC
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/million cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% NaN3, 0.2% BSA)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Flow Cytometry
Flow cytometric analysis of 293T cells with H2AX (phospho Ser139) monoclonal antibody, clone 1E4 (APC)(Cat # MAB23361). Unstained as negative control (blue) or untreated (red) or treated with UV and TPA (green). -
Gene Info — H2AFX
Entrez GeneID
3014Protein Accession#
P16104Gene Name
H2AFX
Gene Alias
H2A.X, H2A/X, H2AX
Gene Description
H2A histone family, member X
Omim ID
601772Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq
Other Designations
H2AX histone
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com