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Last updated: 2023/5/29

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LMAN1 monoclonal antibody, clone AEBI-12 

  • Catalog # : MAB22290
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic protein of human LMAN1.
  • Immunogen:
  • A synthetic peptide corresponding to human LMAN1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human, mouse, rat LMAN1, in native form and recombinant. Superfamily members of LMAN1 are not reactive to antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1:50-200)
    Western Blot (1:500-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of (1) HeLa , (2) Jurkat cell lysates.
  • Immunofluorescence
  • Application Image
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3998
  • Gene Name:
  • LMAN1
  • Gene Alias:
  • ERGIC-53,ERGIC53,F5F8D,FMFD1,MCFD1,MR60,gp58
  • Gene Description:
  • lectin, mannose-binding, 1
  • Gene Summary:
  • The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq
  • Other Designations:
  • coagulation factor V-factor VIII combined deficiency,endoplasmic reticulum-golgi intermediate compartment protein 53,intracellular mannose specific lectin
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