SLC7A11 monoclonal antibody, clone ACGI-19
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SLC7A11.
Immunogen
A synthetic peptide corresponding to human SLC7A11.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
The antibody reacts with human, mouse SLC7A11, in native form and recombinant. Superfamily members of SLC7A11 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: HepG2 cell lysate; Lane 2: Mouse brain lysate.Immunoprecipitation
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Gene Info — SLC7A11
Entrez GeneID
23657Protein Accession#
Q9UPY5Gene Name
SLC7A11
Gene Alias
CCBR1, xCT
Gene Description
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
Omim ID
607933Gene Ontology
HyperlinkGene Summary
SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate.[supplied by OMIM
Other Designations
cystine/glutamate transporter
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