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XRCC1 monoclonal antibody, clone ABOH-24 

  • Catalog # : MAB22064
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic protein of human XRCC1.
  • Immunogen:
  • A synthetic peptide corresponding to human XRCC1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody reacts with human, mouse, rat XRCC1, in native form and recombinant. Superfamily members of XRCC1 are not reactive to antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
    Immunofluorescence (1:50-200)
    Immunocytochemistry (1:50-200)
    Western Blot (1:500-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (cell lysate) analysis of HeLa cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 7515
  • Gene Name:
  • XRCC1
  • Gene Alias:
  • RCC
  • Gene Description:
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • Gene Summary:
  • The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
  • Other Designations:
  • DNA repair protein XRCC1,X-ray repair cross complementing protein 1,X-ray-repair, complementing defective, repair in Chinese hamster
  • Gene Pathway
  • Related Disease
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