SRSF1 monoclonal antibody, clone ADGH-19
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of mouse spleen lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human SRSF1.
Immunogen
A synthetic peptide corresponding to human SRSF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat SRSF1, in native form and recombinant. Superfamily members of SRSF1 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-500)
Immunofluorescence (1:50-200)
Immunocytochemistry (1:50-200)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of mouse spleen lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — SFRS1
Entrez GeneID
6426Protein Accession#
Q07955Gene Name
SFRS1
Gene Alias
ASF, MGC5228, SF2, SF2p33, SRp30a
Gene Description
splicing factor, arginine/serine-rich 1
Omim ID
600812Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
pre-mRNA-splicing factor SF2, P33 subunit|splicing factor 2
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