CD53 monoclonal antibody, clone 1H2C7
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD53-hIgGFc transfected HEK293 cell lysates with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CD53.
Immunogen
Recombinant protein corresponding to human CD53.
Host
Mouse
Theoretical MW (kDa)
24.3
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD53-hIgGFc transfected HEK293 cell lysates with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343).Flow Cytometry
Flow cytometric analysis of HL-60 cells with CD53 monoclonal antibody, clone 1H2C7 (Cat # MAB21343) (Green). Red: Negative Control. -
Gene Info — CD53
Entrez GeneID
963Protein Accession#
P19397Gene Name
CD53
Gene Alias
MOX44, TSPAN25
Gene Description
CD53 molecule
Omim ID
151525Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
CD53 antigen|CD53 glycoprotein|CD53 tetraspan antigen|OTTHUMP00000013686|OTTHUMP00000059505|antigen MOX44 identified by monoclonal antibody MRC-OX44|cell surface antigen|leukocyte surface antigen CD53|tetraspanin-25|transmembrane glycoprotein
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Interactome
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Disease
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