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Last updated: 2023/5/29

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TIA1 monoclonal antibody, clone AAHD-20 

  • Catalog # : MAB20784
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human TIA1.
  • Immunogen:
  • A synthetic peptide corresponding to human TIA1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42.963
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:50-1:200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: Jurkat and Lane 2: NIH/3T3 cell lysates with TIA1 monoclonal antibody, clone AAHD-20 (Cat # MAB20784).
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 7072
  • Gene Name:
  • TIA1
  • Gene Alias:
  • -
  • Gene Description:
  • TIA1 cytotoxic granule-associated RNA binding protein
  • Gene Summary:
  • The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq
  • Other Designations:
  • T-cell-restricted intracellular antigen-1,TIA1 cytotoxic granule-associated RNA-binding protein,TIA1 protein,cytotoxic granule-associated RNA-binding protein,nucleolysin TIA-1 isoform p40,p40-TIA-1 (containing p15-TIA-1)
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