Rabbit monoclonal antibody raised against synthetic peptide of human SIRT2.
Immunogen:
A synthetic peptide corresponding to human SIRT2.
Host:
Rabbit
Theoretical MW (kDa):
43.182
Reactivity:
Human
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Flow Cytometry (1:30) Immunocytochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) Immunoprecipitation (1:50) Western Blot (1:50-1:2000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction:
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq
Other Designations:
silencing information regulator 2-like,silent information regulator 2,sir2-related protein type 2,sirtuin 2,sirtuin type 2