LOX monoclonal antibody, clone ABEO-12
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human LOX.
Immunogen
A synthetic peptide corresponding to human LOX.
Host
Rabbit
Theoretical MW (kDa)
46.944
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:60)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: Jurkat cell and Lane 2: mouse brain tissue lysates with LOX monoclonal antibody, clone ABEO-12 (Cat # MAB20452).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Flow Cytometry
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Gene Info — LOX
Entrez GeneID
4015Protein Accession#
P28300Gene Name
LOX
Gene Alias
MGC105112
Gene Description
lysyl oxidase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. [provided by RefSeq
Other Designations
protein-lysine 6-oxidase
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Interactome
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Disease
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