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Last updated: 2023/5/29

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ERBB4 monoclonal antibody, clone GGB-5 

  • Catalog # : MAB20017
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human ERBB4.
  • Immunogen:
  • A synthetic peptide corresponding to human ERBB4.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 146.808
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot analysis of human brain tissue lysate with ERBB4 monoclonal antibody, clone GGB-5 (Cat # MAB20017).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2066
  • Gene Name:
  • ERBB4
  • Gene Alias:
  • HER4,MGC138404,p180erbB4
  • Gene Description:
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • Gene Summary:
  • This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
  • Other Designations:
  • avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4,receptor tyrosine-protein kinase erbB-4,tyrosine kinase-type cell surface receptor HER4,v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4,v-erb-a erythroblastic leukemia v
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