SLC1A2 monoclonal antibody, clone ABED-19
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More Files
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Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with SLC1A2 monoclonal antibody, clone ABED-19 (Cat # MAB20001).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SLC1A2.
Immunogen
A synthetic peptide corresponding to human SLC1A2.
Host
Rabbit
Theoretical MW (kDa)
62.104
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with SLC1A2 monoclonal antibody, clone ABED-19 (Cat # MAB20001).Immunoprecipitation
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Gene Info — SLC1A2
Entrez GeneID
6506Protein Accession#
P43004Gene Name
SLC1A2
Gene Alias
EAAT2, GLT-1
Gene Description
solute carrier family 1 (glial high affinity glutamate transporter), member 2
Omim ID
600300Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glial high affinity glutamate transporter|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2|solute carrier family 1, member 2
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Interactome
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Pathway
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Disease
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Publication Reference
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α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
Pan Wang, Guoyu Lan, Bin Xu, Zhenwei Yu, Chen Tian, Xia Lei, Wassilios G Meissner, Tao Feng, Ying Yang, Jing Zhang.
Translational Neurodegeneration 2023 Aug; 12(1):40.
Application：Incubation, IP, WB, Human, Mouse, Human plasma, Mouse brain.
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α-Synuclein-carrying astrocytic extracellular vesicles in Parkinson pathogenesis and diagnosis.
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