BCL6 monoclonal antibody, clone BAF-2
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Daudi cell lysate with BCL6 monoclonal antibody.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human tonsil with BCL6 monoclonal antibody.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human BCL6.
Immunogen
A synthetic peptide corresponding to human BCL6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Daudi cell lysate with BCL6 monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human tonsil with BCL6 monoclonal antibody.Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — BCL6
Entrez GeneID
604Protein Accession#
P41182Gene Name
BCL6
Gene Alias
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Gene Description
B-cell CLL/lymphoma 6
Omim ID
109565Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell lymphoma 6 protein|B-cell lymphoma 6 protein transcript|cys-his2 zinc finger transcription factor|lymphoma-associated zinc finger gene on chromosome 3|zinc finger protein 51|zinc finger transcription factor BCL6S
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Interactome
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Disease
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