ACTN2 monoclonal antibody, clone AOCB-1

Catalog # MAB19527

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Size:100 ug
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of HepG2 cell lysate with ACTN2 monoclonal antibody.

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human ACTN2.

    Immunogen

    A synthetic peptide corresponding to human ACTN2.

    Host

    Rabbit

    Reactivity

    Human, Mouse, Rat

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:50-1:200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

    Storage Instruction

    Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of HepG2 cell lysate with ACTN2 monoclonal antibody.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunoprecipitation

  • Gene Info — ACTN2

    Entrez GeneID

    88

    Protein Accession#

    P35609

    Gene Name

    ACTN2

    Gene Alias

    CMD1AA

    Gene Description

    actinin, alpha 2

    Omim ID

    102573

    Gene Ontology

    Hyperlink

    Gene Summary

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq

    Other Designations

    F-actin cross-linking protein|OTTHUMP00000037963|alpha-actinin skeletal muscle

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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