Mouse monoclonal antibody raised against partial recombinant human SPTBN4.
Immunogen:
Recombinant protein corresponding to amino acids 1621-1832 at C-terminus of human SPTBN4.
Host:
Mouse
Reactivity:
Human
Form:
Liquid
Conjugation:
FITC
Purification:
Protein G purification
Isotype:
IgG1
Recommend Usage:
Immunocytochemistry Immunofluorescence Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS/Bicarbonate.
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq