KRT7 monoclonal antibody, clone R17-S
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human pancreatic tissue (4 um) stained with KRT7 monoclonal antibody, clone R17-S (Cat # MAB1657) shows positive immunostaining of pancreatic adenocarcinoma. Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of KRT7.
Immunogen
A synthetic peptide corresponding to N-terminus of human KRT7.
Host
Rabbit
Reactivity
Human
Form
Liquid
Isotype
IgG
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl, pH 8.0 (20 mg/mL BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human pancreatic tissue (4 um) stained with KRT7 monoclonal antibody, clone R17-S (Cat # MAB1657) shows positive immunostaining of pancreatic adenocarcinoma. Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia. -
Gene Info — KRT7
Entrez GeneID
3855Gene Name
KRT7
Gene Alias
CK7, K2C7, K7, MGC129731, MGC3625, SCL
Gene Description
keratin 7
Omim ID
148059Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
Other Designations
cytokeratin 7|keratin, 55K type II cytoskeletal|keratin, simple epithelial type I, K7|keratin, type II cytoskeletal 7|sarcolectin|type II mesothelial keratin K7
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