IL10 monoclonal antibody, clone mxsghk-10
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant IL10.
Immunogen
Recombinant protein corresponding to human IL10.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Isotype
IgG1
Recommend Usage
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS.
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with 0.5 mL of deionized water, mix gently, wash the sides of the vial and wait 30-60 seconds before use. If not intended for use within a month, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL10
Entrez GeneID
3586Gene Name
IL10
Gene Alias
CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
Gene Description
interleukin 10
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
Other Designations
cytokine synthesis inhibitory factor
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Interactome
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Pathway
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Disease
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