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Last updated: 2023/3/26

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TIMP2 monoclonal antibody, clone F27P3A4 

  • Catalog # : MAB12521
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human TIMP2.
  • Immunogen:
  • A synthetic peptide corresponding to human TIMP2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • ELISA
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 - 15 ug/mL)
    Western Blot (1 - 2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of TIMP2 recombinant protein with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast with TIMP2 monoclonal antibody, clone F27P3A4 (Cat # MAB12521) at 10 ug/mL working concentration.
  • Enzyme-linked Immunoabsorbent Assay
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Gene Information
  • Entrez GeneID:
  • 7077
  • Gene Name:
  • TIMP2
  • Gene Alias:
  • CSC-21K
  • Gene Description:
  • TIMP metallopeptidase inhibitor 2
  • Gene Summary:
  • This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq
  • Other Designations:
  • tissue inhibitor of metalloproteinase 2,tissue inhibitor of metalloproteinases 2
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