TNFRSF8 monoclonal antibody, clone CD30/412
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of Hodgkin's lymphoma using TNFRSF8 monoclonal antibody, clone CD30/412 (Cat # MAB11230).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant TNFRSF8.
Immunogen
Recombinant protein corresponding to human TNFRSF8.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G affinity chromatography
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of Hodgkin's lymphoma using TNFRSF8 monoclonal antibody, clone CD30/412 (Cat # MAB11230). -
Gene Info — TNFRSF8
Entrez GeneID
943Protein Accession#
NP_001234Gene Name
TNFRSF8
Gene Alias
CD30, D1S166E, KI-1
Gene Description
tumor necrosis factor receptor superfamily, member 8
Omim ID
153243Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD30 antigen|CD30L receptor|Ki-1 antigen|OTTHUMP00000001783|cytokine receptor CD30|lymphocyte activation antigen CD30
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Interactome
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Pathway
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Disease
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