BMX monoclonal antibody, clone 1C6
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant BMX.
Immunogen
Recombinant protein corresponding to human BMX.
Host
Mouse
Theoretical MW (kDa)
78
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using BMX monoclonal antibody, clone 1C6 (Cat # MAB10508) against BMX-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — BMX
Entrez GeneID
660Gene Name
BMX
Gene Alias
ETK, PSCTK2, PSCTK3
Gene Description
BMX non-receptor tyrosine kinase
Omim ID
300101Gene Ontology
HyperlinkGene Summary
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified
Other Designations
OTTHUMP00000022964|OTTHUMP00000022965|OTTHUMP00000022966
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Interactome
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Disease
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