CD80 monoclonal antibody, clone 2A2
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant CD80.
Immunogen
Recombinant protein corresponding to human CD80.
Host
Mouse
Theoretical MW (kDa)
55
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascitic (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using CD80 monoclonal antibody, clone 2A2 (Cat # MAB10424).Immunofluorescence
Confocal immunofluorescence analysis of BCBL-1 cells using CD80 monoclonal antibody, clone 2A2 (Cat # MAB10424) (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CD80
Entrez GeneID
941Gene Name
CD80
Gene Alias
CD28LG, CD28LG1, LAB7
Gene Description
CD80 molecule
Omim ID
112203Gene Ontology
HyperlinkGene Summary
The B-lymphocyte activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.[supplied by OMIM
Other Designations
B-lymphocyte activation antigen B7|CD80 antigen|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
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Interactome
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Pathway
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Disease
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