Mouse monoclonal antibody raised against native CR2.
Immunogen:
Native purified CR2 from human B-lymphoblastoid cell line IM9.CR2.
Host:
Mouse
Theoretical MW (kDa):
145
Reactivity:
Bovine, Human, Pig
Specificity:
This antibody reacts with CD21 (CR2), a 145 KDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
Form:
Liquid
Purification:
Protein-A affinity chromatography.
Isotype:
IgG1
Recommend Usage:
The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction:
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Complement component receptor-2 (CR2) is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. See also CR1 (MIM 120620). Yefenof et al. (1976) [PubMed 181330] found complete overlapping of EBV receptors and C3 (MIM 120700) receptors on human B lymphocytes.[supplied by OMIM