ITGB1 monoclonal antibody, clone MEM-101A
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More Files
- More Functions
Western Blot (Cell lysate)
Western blotting analysis (non - reducing conditions) of isolated peripheral blood lymphocytes of various species using ITGB1 monoclonal antibody, clone MEM - 101A (Cat # MAB0883) . Lane 1 : Lysate of human PBL. Lane 2 : Lysate of canine PBL. Lane 3 : Lysate of porcine PBL.
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Specification
Product Description
Mouse monoclonal antibody raised against native ITGB1.
Immunogen
Native purified ITGB1 from leukocytes of a patient suffering from a LGL-type leukemia.
Host
Mouse
Theoretical MW (kDa)
130
Reactivity
Dog, Human, Pig
Specificity
This antibody reacts with CD29 (integrin beta chain), a 130 KDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blotting analysis (non - reducing conditions) of isolated peripheral blood lymphocytes of various species using ITGB1 monoclonal antibody, clone MEM - 101A (Cat # MAB0883) . Lane 1 : Lysate of human PBL. Lane 2 : Lysate of canine PBL. Lane 3 : Lysate of porcine PBL.Immunoprecipitation
Flow Cytometry
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Gene Info — ITGB1
Entrez GeneID
3688Gene Name
ITGB1
Gene Alias
CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
Gene Description
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Omim ID
135630Gene Ontology
HyperlinkGene Summary
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000019420|OTTHUMP00000046253|OTTHUMP00000063731|OTTHUMP00000063732|OTTHUMP00000063733|fibronectin receptor beta subunit|integrin VLA-4 beta subunit|integrin beta 1
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Interactome
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Pathway
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Disease
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