Anti-Natalizumab (Human) ELISA Kit (Quantitative)
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Specification
Product Description
Anti-Natalizumab (Human) ELISA Kit (Quantitative) is a quantitative determination of antibodies to Natalizumab in serum and plasma.
Suitable Sample
Serum or Plasma
Sample Volume
10 uL
Label
HRP-conjugate
Absorbance (nm)
450/650 nm
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
3.125 - 50 ng/mL
Limit of Detection
1.87 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — CSH1
Entrez GeneID
1442Gene Name
CSH1
Gene Alias
CSA, CSMT, FLJ75407, PL
Gene Description
chorionic somatomammotropin hormone 1 (placental lactogen)
Omim ID
150200Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq
Other Designations
CS-1|choriomammotropin|chorionic somatomammotropin A|chorionic somatomammotropin hormone 1|hCS-A|placental lactogen
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Gene Info — ITGA4
Entrez GeneID
3676Gene Name
ITGA4
Gene Alias
CD49D, IA4, MGC90518
Gene Description
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Omim ID
192975Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq
Other Designations
269C wild type|antigen CD49D, alpha-4 subunit of VLA-4 receptor|integrin alpha 4|integrin alpha-4 subunit|very late activation protein 4 receptor, alpha 4 subunit
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Interactome
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Pathway
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Cell adhesion molecules (CAMs)
- Cytokine-cytokine receptor interaction
- ECM-receptor interaction
- Focal adhesion
- Hematopoietic cell lineage
- Hypertrophic cardiomyopathy (HCM)
- Jak-STAT signaling pathway
- Leukocyte transendothelial migration
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Disease
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