CD27 (Human) ELISA Kit
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The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
CD27 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CD27.
Suitable Sample
Cell culture supernates, Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
62.5 to 4000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — CD27
Entrez GeneID
939Gene Name
CD27
Gene Alias
MGC20393, S152, T14, TNFRSF7, Tp55
Gene Description
CD27 molecule
Omim ID
186711Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
Other Designations
CD27 antigen|CD27L receptor|T cell activation antigen CD27|T cell antivation antigen S152|tumor necrosis factor receptor superfamily, member 7
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Interactome
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Pathway
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Disease
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Publication Reference
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Increased CD27 Expression in the Skins and Sera of Patients With Systemic Sclerosis.
Yuka Oshikawa, Takamitsu Makino, Miri Nakayama, Soichiro Sawamura, Katsunari Makino, Ikko Kajihara, Jun Aoi, Shinichi Masuguchi, Satoshi Fukushima, Hironobu Ihn.
Intractable & Rare Diseases Research 2020 May; 9(2):99.
Application：Quant, Human, Human serum.
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Increased CD27 Expression in the Skins and Sera of Patients With Systemic Sclerosis.
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