C2 (Human) ELISA Kit
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Specification
Product Description
C2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human C2.
Suitable Sample
Cell Culture Supernatant, Cell lysate, CSF, Plasma, Saliva, Serum, Milk
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
6.25 to 400 ng/mL
Reactivity
Human, Monkey
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C. For long term storage, please store at -20°C.
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Applications
Quantification
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Gene Info — C2
Entrez GeneID
717Gene Name
C2
Gene Alias
CO2, DKFZp779M0311
Gene Description
complement component 2
Gene Ontology
HyperlinkGene Summary
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
Other Designations
C3/C5 convertase|OTTHUMP00000029277|OTTHUMP00000062690|complement C2|complement component C2
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Interactome
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Pathway
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Disease
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