CXCL11 (Human) is a sandwich enzyme immunoassay for the quantitative measurement of human CXCL11.
Calibration Range:
31.2 to 2000 pg/ml
Reactivity:
Human
Quality Control Testing:
Standard curve
The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction:
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. [provided by RefSeq
Other Designations:
small inducible cytokine B11,small inducible cytokine subfamily B (Cys-X-Cys), member 11,small inducible cytokine subfamily B (Cys-X-Cys), member 9B