A2M (Human) ELISA Kit
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Specification
Product Description
A2M (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human A2M.
Suitable Sample
Cell Culture Supernatant, CSF, Milk, Saliva
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1.953 to 500 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — A2M
Entrez GeneID
2Gene Name
A2M
Gene Alias
CPAMD5, DKFZp779B086, FWP007, S863-7
Gene Description
alpha-2-macroglobulin
Gene Ontology
HyperlinkGene Summary
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Cross talk between primary human renal tubular cells and endothelial cells in cocultures.
Tasnim F, Zink D.
American Journal of Physiology. Renal Physiology 2012 Apr; 302(8):F1055.
Application:ELISA, Human, HPTC and HUVEC culture medium.
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Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis.
Pineda-Salgado L, Craig EJ, Blank RB, Kessler DS.
Gene Expression Patterns 2015 Dec; 6(1):3.
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Glomerular deposition of alpha 2-macroglobulin in glomerular diseases.
Yang AH, Chen JY.
Nephrology, Dialysis, Transplantation 1997 Mar; 12(3):465.
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Hepatocyte growth factor and acute phase proteins in patients with chronic liver diseases.
Shiota G, Umeki K, Okano J, Kawasaki H.
J Med 1995 Jan; 26(5-6):295.
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Cross talk between primary human renal tubular cells and endothelial cells in cocultures.
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