SERPINA1 (Human) ELISA Kit
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Specification
Product Description
SERPINA1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human SERPINA1.
Suitable Sample
Cell Culture Supernatant, Cell Lysate, CSF, Milk, Plasma, Saliva, Serum, Urine
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.391 to 25 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — SERPINA1
Entrez GeneID
5265Gene Name
SERPINA1
Gene Alias
A1A, A1AT, AAT, MGC23330, MGC9222, PI, PI1, PRO2275
Gene Description
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serine proteinase inhibitor, clade A, member 1
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Interactome
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Pathway
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Disease
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Publication Reference
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iTRAQ-based proteomic analysis reveals potential regulatory networks in dust mite-related asthma treated with subcutaneous allergen immunotherapy.
Jun Bai, Jia-Yong Zhong, Wang Liao, Ruo Hu, Liang Chen, Xian-Jin Wu, Shuang-Ping Liu.
Molecular MedicineRreports 2020 Nov; 22(5):3607.
Application:Quant, Human, Human serum.
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Results of a survey of patients with alpha-1 antitrypsin deficiency.
Strange C, Stoller JK, Sandhaus RA, Dickson R, Turino G.
Respiration 2006 Aug; 73(2):185.
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Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome?
Abboud RT, Ford GT, Chapman KR.
Treatments in Respiratory Medicine 2005 Feb; 4(1):1.
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Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.
Chappell S, Guetta-Baranes T, Batowski K, Yiannakis E, Morgan K, O'Connor C, MacNee W, Kalsheker N.
Human Mutation 2004 Dec; 24(6):535.
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iTRAQ-based proteomic analysis reveals potential regulatory networks in dust mite-related asthma treated with subcutaneous allergen immunotherapy.
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