TIMP3 (Human) ELISA Kit
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Specification
Product Description
TIMP3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human TIMP3.
Suitable Sample
Cell Culture Supernatant, Plasma (EDTA, Heparin), Serum, Saliva
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
156 to 10000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — TIMP3
Entrez GeneID
7078Gene Name
TIMP3
Gene Alias
HSMRK222, K222, K222TA2, SFD
Gene Description
TIMP metallopeptidase inhibitor 3
Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq
Other Designations
MIG-5 protein|tissue inhibitor of metalloproteinase 3
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Interactome
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Disease
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Publication Reference
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Oxysterol-induced soluble endoglin release and its involvement in hypertension.
Valbuena-Diez AC, Blanco FJ, Oujo B, Langa C, Gonzalez-Nuñez M, Llano E, Pendas AM, Díaz M, Castrillo A, Lopez-Novoa JM, Bernabeu C.
Circulation 2012 Nov; 126(22):2612.
Application:ELISA, Human, JAR cells culture medium.
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Transcriptional regulation of TIMPs in ascending aorta aneurysms.
Tsarouhas K, Soufla G, Apostolakis S, Zaravinos A, Panagiotou M, Khoury M, Hassoulas JA, Tsatsakis AM, Spandidos DA.
Thrombosis Research 2010 Nov; 126(5):399.
Application:ELISA, Human, Aortic tissue.
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Genomic organization of the human tissue inhibitor of metalloproteinases-3 (TIMP3).
Stohr H, Roomp K, Felbor U, Weber BH.
Genome Research 1995 Dec; 5(5):483.
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Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22.
Apte SS, Mattei MG, Olsen BR.
Genomics 1994 Jan; 19(1):86.
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Oxysterol-induced soluble endoglin release and its involvement in hypertension.
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