FLCN polyclonal antibody (A02)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant FLCN.
Immunogen
FLCN (AAH15687, 1 a.a. ~ 342 a.a) full-length recombinant protein with GST tag.
Sequence
MNAIVALCHFCELHGPRTLFCTEVLHAPLPQGDGNEDSPGQGEQAEEEEGGIQMNSRMRAHSPAEGASVESSSPGPKKSDMCEGCRSLAAGHPGYISHDKETSIKYVSHQHPSHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSWPFLLGKVRGIIDELQGKALKVFEAEQFGCPQRAQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLTEKLLEGAPTEDTLVQMEKLAGEAGVLLPGPWPGWPWGGTSCLLSWQESLREGNAALNQPRTSLREAHPPISV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (63.36 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — FLCN
Entrez GeneID
201163GeneBank Accession#
BC015687Protein Accession#
AAH15687Gene Name
FLCN
Gene Alias
BHD, DKFZp547A118, FLCL, FLJ45004, FLJ99377, MGC17998, MGC23445
Gene Description
folliculin
Gene Ontology
HyperlinkGene Summary
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Birt Hogg-Dube syndrome associated FLCN mutations disrupt protein stability.
Nahorski MS, Reiman A, Lim DH, Nookala RK, Seabra L, Lu X, Fenton J, Boora U, Nordenskjold M, Latif F, Hurst LD, Maher ER.
Human Mutation 2011 Aug; 32(8):921.
Application:WB-Tr, Human, FTC-133 cells.
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Birt Hogg-Dube syndrome associated FLCN mutations disrupt protein stability.
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